发明名称 |
SYSTEMS AND METHODS FOR TREATING HUMAN INFLAMMATORY AND PROLIFERATIVE DISEASES, WITH A COMBINATION OF FATTY ACID METABOLISM INHIBITORS AND GLYCOLYTIC INHIBITORS AND/OR UCP AND/OR FAS ANTIBODIES |
摘要 |
The present invention generally relates to systems and methods for treating inflammatory and proliferative diseases, and wounds, using a combination of (1) fatty acid metabolism inhibitors and (2) glycolytic inhibitors and/or UCP and/or Fas inhibitors or antibodies. More particularly, the invention combines an oxirane carboxylic acid compound, represented by etomoxir, with a 2-deoxyglucose compound, represented by 2-deoxy-D-glucose, and/or an antibody against UCP and/or Fas antigen. The systems and methods of the invention can be used to treat drug-resistant or multi-drug resistant cancers (i.e., cancers resistant to conventional cancer drug therapies). |
申请公布号 |
WO2005107801(A3) |
申请公布日期 |
2008.06.26 |
申请号 |
WO2005US15032 |
申请日期 |
2005.04.28 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
NEWELL, KAREN, ROGERS, M. |
分类号 |
A61K31/675;A01N43/04;A61K31/335;A61K39/395;C07K16/28 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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