发明名称 METHODS FOR DETECTION AND MEASUREMENT OF SECRETORY PHOSPHOLIPASE A2 LEVELS (sPLA2) IN BIOLOGICAL FLUIDS
摘要 <p>Elevated levels of secretory phospholipase A2 (sPLA&lt;SUB&gt;2&lt;/SUB&gt;) are associated with a variety of inflammatory conditions, e.g., multiple sclerosis, arteriosclerosis, rheumatoid arthritis, osteoarthritis and sickle cell. ELISA-based assays have been developed for detecting and measuring sPLA&lt;SUB&gt;2&lt;/SUB&gt; levels in biological fluids, but these methods are too time-consuming for practical clinical diagnostic use. Disclosed herein in certain embodiments are methods for rapid detection and measurement of sPLA&lt;SUB&gt;2&lt;/SUB&gt; levels (e.g., sPLA&lt;SUB&gt;2&lt;/SUB&gt; type IIA) in a biological fluid generally, and methods for detection and measurement of sPLA&lt;SUB&gt;2&lt;/SUB&gt; levels in urine.</p>
申请公布号 WO2008076994(A2) 申请公布日期 2008.06.26
申请号 WO2007US87819 申请日期 2007.12.17
申请人 ANTHERA PHARMACEUTICALS, INC.;TRUEX, PAUL;TRIAS, JOAQUIM 发明人 TRUEX, PAUL;TRIAS, JOAQUIM
分类号 C12Q1/46 主分类号 C12Q1/46
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