Disclosed herein are zinc fingers comprising CCHC zinc coordinating resid ues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are als o described
申请公布号
CA2669746(A1)
申请公布日期
2008.06.26
申请号
CA20072669746
申请日期
2007.12.13
申请人
DOW AGROSCIENCES LLC;SANGAMO BIOSCIENCES, INC.
发明人
PETOLINO, JOSEPH F.;BAKER, LISA W.;GARRISON, ROBBI J.;SHUKLA, VIPULA K.;BLUE, RYAN C.;MILLER, JEFFREY;WORDEN, SARAH E.;URNOV, FYODOR;CAI, QIHUA C.;ARNOLD, NICOLE L.;MITCHELL, JON C.