发明名称 |
C CRP precptor antagonisists |
摘要 |
Compounds of Formula (I): and Formula (II): (where variables R<2>, R<4>, A, B, D, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. |
申请公布号 |
ZA200702309(B) |
申请公布日期 |
2008.06.25 |
申请号 |
ZA20070002309 |
申请日期 |
2007.03.19 |
申请人 |
MERCK & CO., INC. |
发明人 |
BURGEY, CHRISTOPHER S.;SHAW, ANTHONY W.;DENG, ZHENGWU J.;VACCA, JOSEPH P.;POTTEIGER, CRAIG M.;PAONE, DANIEL V.;NGUYEN, DIEM N.;WILLIAMS, THERESA M.;SELNICK, HAROLD G |
分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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