PHARMACEUTICAL COMPOSITIONS COMPRISING COMBINED ANTIDIABETIC SUBSTANCES FOR USE IN DIABETES MELLITUS

摘要

The present invention relates to the pharmaceutical industry in general and, in particular, to the pharmaceutical industry involved in the preparation of medicaments for controlling diabetes. More specifically, the invention relates to a composition comprising different types of antidiabetic substances in combination. The composition is characterized in that the aforementioned combination or association consists of two or three antidiabetic substances that are selected from the group containing: sulfonylureas, meglitinides, biguanides or inhibitors of alpha-glucosidase with thiazolidinediones for the treatment of type 2 diabetes mellitus in novel formulations and wherein the sulfonylureas are selected from the group containing glipizide, glyburide, glimepiride; meglitinides, repaglinide, nateglinide, thiazolidinediones or a combination of same; biguanides such as metformin; inhibitors of alpha-glucosidase known as acarbose, miglitol associated or combined with thiazolidinediones known as pioglitazone, rosiglitazone, troglitazone, such as a base or a physiologically-accepted salt.