发明名称 Process for preparing 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid
摘要 The present invention relates to a process for the preparation of 1-(2-ethyl-butyl)- cyclohexanecarboxylic acid which is useful as an intermediate in the preparation of pharmaceutical active compounds, wherein cyclohexanecarboxylic acid alkali metal salt reacts with an alkylating agent in the presence of a secondary amine and (C 1 -C 6 ) alkyllithium, (C 3 -C 6 ) cycloalkyllithium or phenyllithium.
申请公布号 EP1935867(A1) 申请公布日期 2008.06.25
申请号 EP20060126724 申请日期 2006.12.20
申请人 F. HOFFMANN-LA ROCHE AG 发明人 LOHRI, BRUNO DR.;HOFFMANN, URSULA
分类号 C07C51/353;C07C61/08 主分类号 C07C51/353
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