Oral immediate release formulation of a poorly water-soluble active substance
摘要
The invention is related to an oral immediate release formulation of Benzazepin-1-acetic acid derivatives comprising a) said active substance in an amount of up to 65% of the total weight of the formulation; b) at least 10% w/w an alkaline compound or a mixture of alkaline compounds; c) between 0.1 and 10% of one or more surfactants, and d) optionally comprises auxiliary materials an amount of between 1% and 45% of the total weight of the formulation.
申请公布号
ZA200705021(B)
申请公布日期
2008.06.25
申请号
ZA20070005021
申请日期
2007.06.04
申请人
SOLVAY PHARMACEUTICALS B.V.;PANACEA BIOTEC LTD.
发明人
SINGH, SUKHJEET;KUMAR, ROHIT;JAIN, RAJESH;DE WINTER, MARIUS L