发明名称 |
METHOD OF CONTROLLING DECOMPOSITION OF PROTEIN BY TETRACYCLINE ANTIBIOTIC |
摘要 |
The present invention provides a fusion protein comprising a variant protein of a protein binding to an antibiotic and a target protein having fused thereto, wherein the variant protein is degraded when the antibiotic is not bound but stabilized when the antibiotic is bound in a cell, and the fusion protein is degraded when the antibiotic is not bound but stabilized when the antibiotic is bound in a cell.
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申请公布号 |
EP1935978(A1) |
申请公布日期 |
2008.06.25 |
申请号 |
EP20060798170 |
申请日期 |
2006.09.14 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
MIWA, YOSHIHIRO |
分类号 |
A61K48/00;C12N15/09;A61K45/00;A61K49/00;A61P35/00;A61P37/02;C07K14/245;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12Q1/02 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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