发明名称 |
Matrix type sustained-release preparation containing basic drug or salt thereof, and method for manufacturing the same |
摘要 |
The present invention provides a method for stabilizing an anti-dementia drug in a pharmaceutical composition containing the anti-dementia drug and a high molecular weight basic substance by adding a high molecular weight acidic substance to said pharmaceutical composition. Further, the present invention provides a pharmaceutical composition containing an anti-dementia drug and a high molecular basic substance in which a high molecular weight acidic substance is contained for stabilizing the anti-dementia drug. Furthermore, the present invention provides a method for manufacturing a pharmaceutical composition which comprises steps wherein a solution or suspension containing a high molecular weight acidic substance is added to a mixture of an anti-dementia drug and a high molecular weight basic substance for the sake of stabilizing the anti-dementia drug. |
申请公布号 |
ZA200705119(B) |
申请公布日期 |
2008.06.25 |
申请号 |
ZA20070005119 |
申请日期 |
2007.06.18 |
申请人 |
EISAI R & D MANAGEMENT CO. LTD. |
发明人 |
UEKI, YOSUKE;FUJIOKA, SATOSHI |
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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