发明名称 Piperidine derivatives and process for their production
摘要 The present invention relates to substantially pure piperidine derivative compounds of the formulae: wherein R<SUB>1 </SUB>is hydrogen or hydroxy; R<SUB>2 </SUB>is hydrogen; or R<SUB>1 </SUB>and R<SUB>2 </SUB>taken together form a second bond between the carbon atoms bearing R<SUB>1 </SUB>and R<SUB>2</SUB>; R<SUB>3 </SUB>is -COOH or -COOR<SUB>4</SUB>; R<SUB>4 </SUB>has 1 to 6 carbon atoms; A, B, and D are the substituents of their respective rings each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, alkoxy, or other substituents. A process of preparing such piperidine derivative compounds in substantially pure form is also disclosed.
申请公布号 US7390906(B2) 申请公布日期 2008.06.24
申请号 US20060455531 申请日期 2006.06.19
申请人 AMR TECHNOLOGY, INC. 发明人 D'AMBRA THOMAS E.
分类号 C07D211/22;A61K31/00;A61K31/445;A61K31/451;A61K31/4515;A61P11/08;A61P27/00;A61P27/14;A61P37/08;C07C59/84;C07C59/86;C07C59/88;C07C59/90;C07C69/738;C07C69/76;C07D211/20;C07D211/32;C07D211/40;C07D211/70 主分类号 C07D211/22
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