发明名称 |
Method for generating primate trophoblasts |
摘要 |
The first method to cause a culture of human and other primate stem cells to directly and uniformly differentiate into a committed cell lineage is disclosed. Treatment of primate stem cells with a single protein trophoblast induction factor causes the cells to transform into human trophoblast cells, the precursor cells of the placenta. Several protein factors including bone morphogenic protein 4 (BMP4), BMP2, BMP7, and growth and differentiation factor 5 can serve as trophoblast-inducting factors.
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申请公布号 |
US7390657(B2) |
申请公布日期 |
2008.06.24 |
申请号 |
US20060582773 |
申请日期 |
2006.10.17 |
申请人 |
WICELL RESEARCH INSTITUTE, INC. |
发明人 |
XU REN-HE;THOMSON JAMES A. |
分类号 |
C12N15/85;C12Q1/02;A61K38/18;C12N5/02;C12N5/073;C12N5/10;G01N33/53 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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