| 发明名称 |
ANTIBODY-DRUG CONJUGATES AND METHODS OF USE |
| 摘要 |
The present disclosure provides antibody-drug conjugates that are potent cytotoxins, wherein the drug is linked to the antibody through a linker. The disclosure is also directed to compositions containing the antibody-drug conjugates, and to methods of treatment using them.
|
| 申请公布号 |
KR20080057310(A) |
申请公布日期 |
2008.06.24 |
| 申请号 |
KR20087009646 |
申请日期 |
2008.04.22 |
| 申请人 |
MEDAREX, INC. |
发明人 |
BOYD SHARON ELAINE;CHEN LIANG;GANGWAR SANJEEV;GUERLAVAIS VINCENT;HORGAN KILIAN;SUFI BILAL;PAN CHIN;KING DAVID JOHN;HUANG HAICHUN;CARDARELLI JOSEPHINE M. |
| 分类号 |
A61K39/395;A61K47/48;A61K48/00;A61P35/00 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
