摘要 |
<P>PROBLEM TO BE SOLVED: To provide an encoded chemical library composed of accumulation of chemical structures defining diversity of biological structures. <P>SOLUTION: An encoded combinatorial chemical library composed of a plurality of bifunctional molecules having both a chemical polymer and an identifier oligonucleotide sequence defining the structure of the chemical polymer, is provided. Further, bifunctional molecules in the library and methods of using the library to identify chemical structures within the library that bind to biologically active molecules in preselected binding interactions, are also provided. <P>COPYRIGHT: (C)2008,JPO&INPIT |