摘要 |
PROBLEM TO BE SOLVED: To preferentially synthesize antimicrobial trans 4-methylthio-3-butenylisothiocyanate. SOLUTION: This method for producing 4-methylthio-3-butenylisothiocyanate comprises producing a carbon atom-halogen atom bond on a methylthio group-bound carbon atom of a 4-methylthiobutylisocyanate [compound (III)] to produce a 4-halogeno-4-methylthiobutylisothiocynate [compound (II)], and then releasing a hydrogen halide to preferentially synthesize the trans 4-methylthio-3-butenylisothiocyanate [compound (I)] of the target compound. COPYRIGHT: (C)2008,JPO&INPIT
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