The present invention concerns methods and compositions for treating or a ssessing treatment of diseases related to mis-expression of genes or genetic pathways that can be modulated by let-7. Methods may include evaluating pat ients for genes or genetic pathways modulated by let-7, and/or using an expr ession profile to assess the condition of a patient or treating the patient with an appropriate miRNA.
申请公布号
CA2671299(A1)
申请公布日期
2008.06.19
申请号
CA20072671299
申请日期
2007.12.10
申请人
ASURAGEN, INC.;YALE UNIVERSITY
发明人
SLACK, FRANK J.;BYROM, MIKE;BROWN, DAVID;JOHNSON, CHARLES D.;OVCHARENKO, DMITRIY;BADER, ANDREAS G.;KELNAR, KEVIN