发明名称 |
Method for Determining Responsiveness to Chk1 Inhibitors |
摘要 |
The invention is directed at a method for predicting a patient's responsiveness to a CHK1 inhibitor The method includes providing a sample from a test patient who is being treated with a DNA damaging agent; and determining for the presence of an activated CHK1 signal transduction pathway molecule, wherein the presence of an activated CHK1 signal transduction pathway molecule is indicative that a CHK1 inhibitor should be administered to the patient.
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申请公布号 |
US2008145358(A1) |
申请公布日期 |
2008.06.19 |
申请号 |
US20060816128 |
申请日期 |
2006.02.16 |
申请人 |
ASTRAZENECA AB |
发明人 |
ZABLUDOFF SONYA;BERGERON LOUISE |
分类号 |
A61K39/395;A61K31/7052;A61K38/02;A61P35/02;C12Q1/48;G01N33/53 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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