Microparticle preparation and medical composition

摘要

According to the present invention, an early-phase release amount of cisplatin (CCDP) is reduced and a release of cisplatin is maintained over a long period of time, such that an anticancer effect against cancer cells is enhanced while side effects are reduced. In this manner, a life prolongation effect for patients is enhanced. A microparticle preparation contains cisplatin that is intercalated into double-helical DNA. The microparticle preparation stably retains cisplatin and exhibits an excellent slow-release property. Accordingly, even when cisplatin containing severe toxicity is used, the side effects can be suppressed and an excellent anticancer effect can be provided over a long period of time.