发明名称 |
INHIBITORS OF PROTEIN PHOSPHATASE 1, GADD34 AND PROTEIN PHOSPHATASE 1/GADD34 COMPLEX, PREPARATION AND USES THEREOF |
摘要 |
The present invention relates to the use of a protein phosphatase inhibitor selected from an inhibitor of the catalytic subunit of the protein phosphatase 1 (PP1), an inhibitor of GADD34 and an inhibitor of the PP1/GADD34 complex to prepare a pharmaceutical composition to prevent or treat a cancer in a mammal, wherein the pharmaceutical composition is intended for administration in combination with a product used in a treatment of a cancer. |
申请公布号 |
WO2008028965(A3) |
申请公布日期 |
2008.06.19 |
申请号 |
WO2007EP59409 |
申请日期 |
2007.09.07 |
申请人 |
INSTITUT GUSTAVE ROUSSY;INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);KROEMER, GUIDO;ZITVOGEL, LAURENCE |
发明人 |
KROEMER, GUIDO;ZITVOGEL, LAURENCE |
分类号 |
A61K31/00;A61K38/17;A61P35/00;C12Q1/00;G01N33/574 |
主分类号 |
A61K31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|