摘要 |
<p>The invention provides a therapeutic method for preventing or treating a pathological condition or symptom in a mammal, such as a human, wherein the infectivity of a pathogen toward mammalian cells is implicated and inhibition of its infectivity is desired comprising administering to a mammal in need of such therapy, an effective amount of an N-benzamide derivative of a piperazinyl amide of an amino acid thereof that inhibits pathogenic infectivity, including pharmaceutically acceptable salts thereof, wherein the pathogen is Avian Influenza, Avian Influenza A, Influenza A, Influenza B, hepatitis B virus, or hepatitis C virus. The invention also provides a therapeutic method for preventing or treating a neuropathological condition or symptom in a mammal, such as human, comprising administering to a mammal in need of such therapy, an effective amount of an N-benzamide derivative of a piperazinyl amide of an amino acid thereof, including pharmaceutically acceptable salts thereof.</p> |
申请人 |
GREESON, JANET;GEORGETOWN UNIVERSITY;SAMARITAN PHARMACEUTICALS, INC.;LECANU, LAURENT;PAPADOPOULOS, VASSILIOS;XU, JING |
发明人 |
LECANU, LAURENT;GREESON, JANET;PAPADOPOULOS, VASSILIOS;XU, JING |