摘要 |
<p>The present teachings provide compounds of Formula (I) wherein Ar, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, X, p and n are defined herein. The present teachings also provide processes for producing said compounds and methods of treating a pathological condition or disorder, or alleviating a symptom thereof, using said compounds. The compounds can be useful in modulating ion channel activity including treating a variety of conditions associated with the abnormal modulation of one or more voltage-gated calcium channels.</p> |
申请人 |
WYETH;ZELLE, ROBERT;MAZDIYASNI, HORMOZ;GALULLO, VINCENT;BAKER, CHRISTOPHER, TODD;WILL, PAUL;GUO, JINSONG;SOENEN, DANIELLE;FENSOME, ANDREW;KERN, JEFFREY, CURTIS;MOORE, WILLIAM, JAY;MELENSKI, EDWARD, GEORGE;KAPLAN, JUSTIN |
发明人 |
ZELLE, ROBERT;MAZDIYASNI, HORMOZ;GALULLO, VINCENT;BAKER, CHRISTOPHER, TODD;WILL, PAUL;GUO, JINSONG;SOENEN, DANIELLE;FENSOME, ANDREW;KERN, JEFFREY, CURTIS;MOORE, WILLIAM, JAY;MELENSKI, EDWARD, GEORGE;KAPLAN, JUSTIN |