| 摘要 |
The present invention relates to a novel use of alpha10, or a heterodimer thereof, for affecting cartilage ECM turnover. Further, it relates to the use of a binding entity binding specifically to alpha10 or a heterodimer thereof in the preparation of a medicament for treating a condition affecting ECM, such as RA and OA. In particular, the invention relates to a method of treating an individual with a condition affecting ECM turnover, comprising administering to the individual an effective amount of a binding agent entity binding specifically to alpha10, or a heterodimer thereof. |
