Bcl-2 family member and BH-3 only proteins for use in development of peptidomimetics

摘要

Embodiments of the present invention relate to the molecular interactions of Bcl-2 family members. The design of peptidomimetics that discriminate between anti-apoptotic and pro-apoptotic Bcl-2 family members and uses the same to modulate apoptosis are described herein.