发明名称 |
MEDICAL DEVICES CONTAINING ORIENTED FILMS OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS |
摘要 |
Continuous processing methods for making absorbable polymeric films with one or more of the following properties: high toughness, low modulus, high tensile strength, and thickness less than 10 mm, more preferably less than 1 mm, and more preferably less than 100 µm, have been developed. In the preferred embodiment, the polymer is a polyhydroxyalkanoate, and in the most preferred embodiment, the polymer comprises 4-hydroxybutyrate. A particularly preferred embodiment is a film of poly-4-hydroxybutyrate or copolymer thereof, wherein the film has a tensile strength greater than 5.5 kgf/mm<SUP>2</SUP>, tensile modulus less than 181 kgf/mm<SUP>2</SUP>, and elongation at break from 10-500%, wherein the film is derived by a continuous process such as melt extrusion or solvent casting, followed by orientation to more than 25% of the film's original length in one or more directions. These can be used for a variety of purposes including fabrication of medical devices. |
申请公布号 |
WO2008070428(A2) |
申请公布日期 |
2008.06.12 |
申请号 |
WO2007US84991 |
申请日期 |
2007.11.16 |
申请人 |
TEPHA, INC.;RIZK, SAID;MARTIN, DAVID, P.;HO, KICHERL;WILLIAMS, SIMON, F. |
发明人 |
RIZK, SAID;MARTIN, DAVID, P.;HO, KICHERL;WILLIAMS, SIMON, F. |
分类号 |
A61L27/18;A61L27/34;A61L31/06;A61L31/10 |
主分类号 |
A61L27/18 |
代理机构 |
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