发明名称 |
Method for treating a disease, disorder or adverse effect caused by an elevated serum concentration of an ugtiai substrate |
摘要 |
The present invention is directed to a method for inducing UGT1A1 isoform expression for treatment of a disease, disorder or adverse effect caused by an elevated serum concentration of an UGT1A1 substrate comprising the step of administering to a subject an effective amount of ritonavir. In particular, the present invention is directed to a method of treating unconjugated hyperbilirubinemia by UGT1A1 induction comprising the step of administering to a subject an effective amount of ritonavir.
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申请公布号 |
US2008138315(A1) |
申请公布日期 |
2008.06.12 |
申请号 |
US20080008964 |
申请日期 |
2008.01.15 |
申请人 |
KEMPF DALE J;BERTZ RICHARD J;WARING JEFFREY F |
发明人 |
KEMPF DALE J.;BERTZ RICHARD J.;WARING JEFFREY F. |
分类号 |
A61K38/20;A61K31/167;A61K31/282;A61K31/427;A61K31/436;A61K31/4418;A61K31/496;A61K31/506;A61K31/551;A61K31/565;A61K31/7048;A61K31/7056;A61K31/7068;A61K31/708;A61K38/21;A61K38/55;A61P7/00 |
主分类号 |
A61K38/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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