| 摘要 |
PROBLEM TO BE SOLVED: To provide an azulene compound capable of being used for treating cancers by modulating protein kinase (PK) activity. SOLUTION: The azulene compound has a formula (I) wherein one of R1, R2, R3, R4, R5, R6, R7 and R8 is 1,3-dihydro-indol-2-one-3-methylene or the like; each of A1, A2, A3, A4, A5, A6, A7, A8, A9, A10, A11 and A12 is independently carbon or nitrogen, with the proviso that maximum two of A1, A2, A3, A4, A5, A6, A7 and A8 are nitrogen atoms and maximum two of A9, A10, A11 and A12 are nitrogen atoms. COPYRIGHT: (C)2008,JPO&INPIT
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