发明名称 INTERNALIZING ANTI-CD74 ANTIBODIES AND METHODS OF USE
摘要 The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.
申请公布号 US2008138333(A1) 申请公布日期 2008.06.12
申请号 US20070754902 申请日期 2007.05.29
申请人 IMMUNOMEDICS, INC. 发明人 HANSEN HANS J.;LEUNG SHUI-ON;QU ZHENGXING;GOLDENBERG DAVID M.
分类号 A61K39/395;A61K31/70;A61K38/21;A61K38/46;A61K39/00;A61K45/00;A61K51/00;A61P17/00;A61P21/00;A61P31/00;A61P35/00;A61P35/02;C07K16/28 主分类号 A61K39/395
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