发明名称 |
Enzymatic Enantioselective Ester or Amide Hydrolysis or Synthesis |
摘要 |
The enantioselectivity of fungal lipolytic enzymes can be altered by substituting a suitably selected amino acid residue. The residue to be substituted is selected from its location in the 3D structure of the enzyme and an ester substrate (or a substrate analogue). A residue in the lid may be selected if it is located close to the acid part or close to the alcohol part of an ester substrate. A residue outside the lid region may be selected if it is located close to the active site or close to the substrate.
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申请公布号 |
US2008138856(A1) |
申请公布日期 |
2008.06.12 |
申请号 |
US20060813614 |
申请日期 |
2006.02.10 |
申请人 |
NOVOZYMES A/S |
发明人 |
SVENDSEN ALLAN;VIND JESPER;BRASK JESPER;DE MARIA LEONARDO |
分类号 |
C12P21/06;C12P7/62 |
主分类号 |
C12P21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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