METHOD AND APPARATUS FOR TRANSMISSION MODE ION/ION DISSOCIATION

摘要

A method an apparatus for analyzing biomolecules is described. The method includes injecting and storing one species of ionized molecule in a linear ion trap and injecting second species of oppositely polarity ionized molecul e such that the second species is transmitted through the stored first speci es. The resultant reaction products may be analyzed by a mass analyzed takin g account of the remaining charge values. In an aspect, a linear ion trap ma y be used as the reaction volume, and the ionized species injected along the axis of the trap in a substantially collinear manner. The mass analysis may be performed by mass selective axial ejection or by a mass spectrometer.