发明名称 |
PROPHYLACTIC/THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE |
摘要 |
<p>Disclosed are: an agent for inhibiting the production of active oxygen from an intestinal epithelium cell; an agent for inhibiting the production of IL-8 from an intestinal epithelium cell; and a prophylactic and therapeutic agent for inflammatory bowel disease and/or irritable bowel syndrome, each of which comprises a fermentation product, a culture supernatant and/or a culture of a bacterium belonging to the genus Bacillus as an active ingredient. The bacterium belonging to the genus Bacillus is preferably Bacillus subtilis, more preferably Bacillus subtilis C-3102 (FERM BP-1096). The agent for inhibiting the production of active oxygen from an intestinal epithelium cell, the agent for inhibiting the production of IL-8 from an intestinal epithelium cell, and the prophylactic and therapeutic agent for inflammatory bowel disease and/or irritable bowel syndrome can be administered through an oral route and are useful for the treatment and prevention of diseases including ulcerative colitis, Crohn's disease and irritable bowel syndrome.</p> |
申请公布号 |
WO2008069102(A1) |
申请公布日期 |
2008.06.12 |
申请号 |
WO2007JP73086 |
申请日期 |
2007.11.29 |
申请人 |
CALPIS CO., LTD.;ROKUTAN, KAZUHITO;KUSUMOTO, KENJI;SUZUKI, HIROMI;FUJIWARA, SHIGERU |
发明人 |
ROKUTAN, KAZUHITO;KUSUMOTO, KENJI;SUZUKI, HIROMI;FUJIWARA, SHIGERU |
分类号 |
A61K35/74;A61P1/04;A61P43/00 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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