| 发明名称 |
MODIFIED LEUKOTOXIN GENE AND PROTEIN |
| 摘要 |
The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, preferably from Mannheimia haemolytica. The modified leukotoxin proteins are useful in vaccine compositions effective against Mannheimia haemolytica in animals.
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| 申请公布号 |
US2008138355(A1) |
申请公布日期 |
2008.06.12 |
| 申请号 |
US20070877134 |
申请日期 |
2007.10.23 |
| 申请人 |
LO REGGIE Y;SHEWEN PATRICIA E;LEE RAYMOND W H;HODGINS DOUG;STROMMER JUDITH N |
发明人 |
LO REGGIE Y.;SHEWEN PATRICIA E.;LEE RAYMOND W.H.;HODGINS DOUG;STROMMER JUDITH N. |
| 分类号 |
A61K39/385;A61K39/00;C07K14/285;C07K14/745;C12N1/21;C12N5/10;C12N15/12;C12N15/63;C12N15/82 |
主分类号 |
A61K39/385 |
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