发明名称 |
Nitroheteroaryl-containing rifamycin derivatives |
摘要 |
Substituted rifamycin derivatives in which a nitroimidazole, nitrothiazole or nitrofuran pharmacophore is covalently bonded to a rifamycin, methods of using the rifamycin derivatives, and pharmaceutical compositions containing the rifamycin derivatives are disclosed. Methods of synthesizing these substituted rifamycin derivatives are also disclosed. The rifamycin derivatives possess antibacterial activity, and are effective against a number of human and veterinary pathogens in the treatment of bacterial diseases.
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申请公布号 |
US2008139577(A1) |
申请公布日期 |
2008.06.12 |
申请号 |
US20070827467 |
申请日期 |
2007.07.12 |
申请人 |
CUMBRE PHARMACEUTICALS INC. |
发明人 |
DING CHARLES Z.;KIM IN HO;WANG JIANCHENG;MA ZHENKUN;JIN YAFEI;COMBRINK KEITH D.;LU GENLIANG;LYNCH A. SIMON |
分类号 |
A61K31/497;A61P31/04;C07D267/00 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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