Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs

摘要

The application provides devices for the disruption of one or more layers of skin. The devices are designed to disrupt a defined area of skin. The defined area can approximate the area that a patch or other suitable vehicle for therapeutic agent, e.g., drug or vaccine, delivery is designed to contact. Exemplary devices employ a mask to define the area to be disrupted. Other devices disrupt a defined area by rotating in place.