A METHOD FOR THE MASS PRODUCTION OF IMMUNOGLOBULIN FC REGION WITH DELETED INITIAL METHIONINE RESIDUES

摘要

Disclosed is a method for the mass production of a monomeric or dimeric immunoglobulin Fc region, free of initial methionine residues, using a recombinant expression vector comprising a nucleotide sequence coding for a recombinant immunoglobulin Fc region comprising an immunoglobulin Fc region linked at the N-terminus thereof to an immunoglobulin Fc region via a peptide bond.