METHODS FOR DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE

摘要

A method of diagnosing a subtype of Crohn's disease in a mammal, comprising:obtaining a sample from the mammal; determining the presence of anti-CBir1 expression in the sample obtained from the mammal; and determining the presence of a perinuclear anti-neutrophil cytoplasmic antibody (pANCA) in the sample obtained from the mammal, wherein the presence of anti-CBir1 expression and the pANCA indicates the subtype of Crohn's disease with features of colitic disease and/or colitic and small bowel disease.