| 发明名称 |
Method for preparing imidazole derivatives |
| 摘要 |
The present invention relates to methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD) by the administration of a composition containing as an active ingredient a compound according to Formula I. In particular, the invention relates to methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the administration of a compound which inhibits malonyl-coenzyme A decarboxylase activity. The present invention also includes within its scope the novel process for the preparation of certain compounds
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| 申请公布号 |
US7385063(B2) |
申请公布日期 |
2008.06.10 |
| 申请号 |
US20030466856 |
申请日期 |
2003.07.21 |
| 申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
ARRHENIUS THOMAS;CHEN MI;CHENG JIE FEI;HUANG YUJIN;NADZAN ALEX MICHAEL;TITH SOVOUTHY;HARAMURA MASAYUKI;WALLACE DAVID MARK;BROWN STEVE JOEL;HARMON CHARLES STANFORD;ZHANG LIN;LOPASCHUK GARY D.;DYCK JASON R. |
| 分类号 |
C07D233/00;C07D295/18;A01N43/50;A61K31/16;A61K31/165;A61K31/166;A61K31/167;A61K31/17;A61K31/175;A61K31/18;A61K31/195;A61K31/197;A61K31/198;A61K31/21;A61K31/215;A61K31/216;A61K31/22;A61K31/221;A61K31/223;A61K31/27;A61K31/275;A61K31/277;A61K31/341;A61K31/381;A61K31/40;A61K31/404;A61K31/41;A61K31/415;A61K31/416;A61K31/4164;A61K31/4172;A61K31/4178;A61K31/4188;A61K31/4196;A61K31/42;A61K31/421;A61K31/4245;A61K31/44;A61K31/4402;A61K31/4409;A61K31/4439;A61K31/444;A61K31/445;A61K31/4453;A61K31/451;A61K31/455;A61K31/495;A61K31/498;A61K31/5375;A61K31/5377;A61P3/04;A61P3/10;A61P3/12;A61P9/00;A61P9/04;A61P9/10;A61P35/00;A61P43/00;C07C33/46;C07C33/48;C07C215/24;C07C233/22;C07C257/22;C07C279/18;C07C307/10;C07C323/14;C07C335/18;C07D209/42;C07D211/14;C07D211/22;C07D213/40;C07D213/56;C07D213/70;C07D213/75;C07D213/81;C07D213/82;C07D231/06;C07D231/12;C07D231/14;C07D231/38;C07D231/40;C07D233/02;C07D233/54;C07D233/64;C07D233/84;C07D233/90;C07D239/42;C07D241/24;C07D257/04;C07D261/04;C07D261/08;C07D261/14;C07D261/18;C07D263/34;C07D271/06;C07D277/46;C07D277/48;C07D277/52;C07D285/12;C07D285/135;C07D295/13;C07D295/194;C07D295/21;C07D295/215;C07D295/22;C07D295/28;C07D307/46;C07D307/52;C07D307/68;C07D333/24;C07D401/04;C07D401/12;C07D403/12;C07D405/12;C07D409/04;C07D413/06;C07D413/12;C07D417/12;C07D417/14;C07D487/08;C07D498/08;C07F9/24;C07F9/40;C07F9/6539 |
主分类号 |
C07D233/00 |
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