发明名称 |
Water soluble paclitaxel prodrugs |
摘要 |
Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
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申请公布号 |
US7384977(B2) |
申请公布日期 |
2008.06.10 |
申请号 |
US20060513390 |
申请日期 |
2006.08.31 |
申请人 |
PG-TXL COMPANY, L.P. |
发明人 |
LI CHUN;WALLACE SIDNEY;YU DONG-FANG;YANG DAVID J. |
分类号 |
A01N37/00;A61K31/21;A61K31/337;A61K41/00;A61K47/48;A61K51/04;A61K51/08;A61L31/10;A61L31/16;C08G73/10 |
主分类号 |
A01N37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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