发明名称 Sensors for biomolecular detection and cell classification
摘要 A sensor device is provided for detecting an analyte in a sample in which an analyte is bound to a detection reagent to form a bound complex. The device comprises (a) a sample ( 5 ) comprising an ionic analyte and a detection reagent in a conductive fluid, wherein the detection reagent has a net charge different from the analyte; (b) a first permeable polymeric hydrogel plate ( 3 ) and a first spacer plate ( 8 ), which plates provide a compartment for the sample; (c) an anode ( 1 ) juxtaposed to the outside of the first hydrogel plate and not in contact with the sample; (d) a cathode ( 9 ) juxtaposed to the outside of the first spacer plate and not in contact with the sample; (e) a voltage generator ( 10 ) to apply an electric potential to the anode and cathode; and (f) a detector ( 11 ). The bound complex formed from the analyte and detection reagent is detected by the detector because the bound complex has a charge that causes it to migrate in a direction opposite from that of the unbound analyte when the electric potential is applied.
申请公布号 US7384781(B2) 申请公布日期 2008.06.10
申请号 US20050231654 申请日期 2005.09.21
申请人 发明人
分类号 C12M1/34;B01L3/00;C12M3/00;C12Q1/68;G01N21/64;G01N33/543 主分类号 C12M1/34
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