发明名称 |
Agonist anti-trk-C monoclonal antibodies |
摘要 |
The invention concerns agonist anti-trkC monoclonal antoibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy. |
申请公布号 |
US7384632(B2) |
申请公布日期 |
2008.06.10 |
申请号 |
US20030312316 |
申请日期 |
2003.10.30 |
申请人 |
GENENTECH, INC. |
发明人 |
DEVAUX BRIGITTE;SHELTON DAVID L.;HONGO JO-ANNE;PRESTA LEONARD G. |
分类号 |
A61K39/00;C12N15/09;A61K39/395;A61K48/00;A61P9/00;A61P25/00;A61P25/02;A61P25/28;C07K16/28;C07K16/32;C12N5/10;C12N15/02;C12N15/13;C12P21/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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