| 摘要 |
A system for detecting interactions between charged targets and analytes. The system includes a fluid channel, and a waveguide associated with the fluid channel. A detection region is associated with the waveguide, and a biasing element is operatively coupled to the detection region. The biasing element is adapted to electrically bias a portion of the waveguide at the detection region, and the charged targets are electrostatically bound to the detection region when the portion of the waveguide is electrically biased. An optical detector is adapted to detect optical changes from the detection region.
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