PROCESS FOR THE SYNTHESIS OF 4-DIFLUOROMETHOXY-8-NITRO-1-FORMYL DIBENZO[B,D] FURAN-AN INTERMEDIATE FOR PDE IV INHIBITORS

摘要

The present invention relates to a process for preparing 4-difluoromethoxy-8- nitro-1-formyl dibenzo[b,d]furan, which is useful as an intermediate for preparing compounds with PDE4 inhibitory activity. The invention further provides a process for preparing a PDE4 inhibitor, such as oglemilast.