发明名称 |
SOLID PHARMACEUTICAL DOSAGE FORMULATIONS |
摘要 |
The present invention features solid pharmaceutical dosage formulations c omprising ritonavir. As a non-limiting example, a dosage form of the present invention comprises a solid dispersion or solid solution of ritonavir in a matrix, where the matrix comprises at least one water-soluble polymer, such as copovidone, and at least one surfactant, such as polyoxyl 40 hydrogenated castor oil or macrogolglycerol hydroxystearate. Preferably, the solid dispe rsion or solution does not include, or includes only an insignificant amount of, PEG.
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申请公布号 |
CA2669938(A1) |
申请公布日期 |
2008.06.05 |
申请号 |
CA20072669938 |
申请日期 |
2007.11.14 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
JUNG, TINA;ALANI, LAMAN;CAI, YAN;GHOSH, SOUMOJEET;FASTNACHT, KATJA;ROSENBERG, JOERG;BERNDL, GUNTHER;LIEPOLD, BERND;BREITENBACH, JOERG;KLEIN, CHERI E.;MORRIS, JOHN;ROTH, WOLFGANG |
分类号 |
A61K9/28;A01N43/54;A01N43/78 |
主分类号 |
A61K9/28 |
代理机构 |
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地址 |
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