| 摘要 |
Apparatuses and methods for the effective implantation of viable cells into the body of a patient. Apparatuses and methods are disclosed that are particularly useful for the effective implantation of viable cells into a patient. The apparatuses preferably include a syringe with a small or zero dead volume, a cannula adapted for cell implantation, and a rotational chamber. The syringe is able to hold a cellular suspension for administration to a patient. The apparatuses and methods also preferably employ a small motor which is adapted to rotate the syringe, cannula, and rotational chamber slowly. That rotation reduces cell clumping in the cellular suspension and better maintains the cellular suspension during the implantation procedure. The apparatuses and methods are particularly well suited for the implantation of neurons into the brain of a patient. The apparatuses and methods may also be used to control the rate and volume of cell delivery during implantation precisely and in an automated manner. The present invention may also be used to delivery small volume fluid suspensions into tissues or cavities of the body. Through the cell or fluid delivery, the apparatuses of the present invention may be used to restore function of the target tissues in patients who have suffered ischemic, toxic, or traumatic injury to the target tissue.
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