摘要 |
<p>Apparatuses and methods are disclosed that are particularly useful for the effective implantation of viable cells into a patient. The apparatuses preferably include a syringe with a small or zero dead volume, a cannula adapted for cell implantation, and a rotational chamber. The syringe is able to hold a cellular suspension for administration to a patient. The apparatuses and methods also preferably employ a small motor which is adapted to rotate the syringe, cannula, and rotational chamber slowly. That rotation reduces cell clumping in the cellular suspension and better maintains the cellular suspension during the implantation procedure. The apparatuses and methods may also be used to control the rate and volume of cell delivery during implantation precisely and in an automated manner. Apparatuses of the present invention may be used to restore function of the target tissues in patients who have suffered ischemic, toxic, or traumatic injury to target tissue.</p> |