<p>A method for reconstructing a functional tooth by using a carrier loaded with a plurality of mesenchymal stem cells including at least one of a stem cell derived from Apical Papilla (SCAP), Periodontal Ligament Stem Cells (PDLSC), and Dental Pulp Stem Cells (DPSC). The mesenchymal stem cell loaded carrier is planted into a site within a subject's oral cavity to form a bio-root upon which a crown may be affixed, The mesenchymal stem cells will develop new periodontal tissues to stabilize the bio-root. Methods disclosed herein are particularly beneficial for subjects lacking good bone structures for conventional crown treatments.</p>
申请公布号
WO2008067488(A2)
申请公布日期
2008.06.05
申请号
WO2007US85971
申请日期
2007.11.29
申请人
UNIVERSITY OF SOUTHERN CALIFORNIA;SHI, SONGTAO;SONOYAMA, WATARU;YAMAZA, TAKAYOSHI;WANG, SONGLIN