PIPERIDINE COMPOUNDS

摘要

The invention relates to piperidine compounds of formula (I) wherein X-R1 represents -N(H)-pyrimidinyl, wherein said pyrimidinyl is unsubstituted or mono-substituted wherein the substituent is selected from (C1-4)alkyl or hal ogen, or X-R1 represents -NH-C(O)-heterocyclyl, wherein the heterocyclyl is selected from benzofuranyl and imidazo[2,1-b]-thiazolyl, wherein said hetero cyclyl is unsubstituted or independently mono-, di-, or tri-substituted wher ein the substituents are independently selected from (C1-4)alkyl; A represen ts a phenyl- or thiazolyl-group, wherein the phenyl or thiazolyl is unsubsti tuted or mono-substituted with (C1-4)alkyl; B represents a phenyl-group, whe rein the phenyl is unsubstituted or mono-, or di- substituted, wherein the s ubstituents are independently selected from the group consisting of (C1-4)al kyl, (C1-4)alkoxy, trifluoromethyl, cyano and halogen; to pharmaceutically a cceptable salts thereof, and to the use of such compounds use as medicaments , especially as orexin receptor antagonists.