摘要 |
A compound represented by the following general formula (1) or a salt thereof or a hydrate of the foregoing is safe while exhibiting suitable physicochemical stability, and is useful as therapeutic or prophylactic agents for diseases associated with thrombus formation. wherein R<SUP>1a</SUP>, R<SUP>1b</SUP>, R<SUP>1c </SUP>and R<SUP>1d </SUP>each independently represent hydrogen, etc., R<SUP>2 </SUP>represents optionally substituted phenyl, etc., R<SUP>3 </SUP>represents optionally substituted C6-10 aryl, etc., Z<SUP>1</SUP>, Z<SUP>2 </SUP>and Z<SUP>3 </SUP>each independently represent hydrogen, etc., Z<SUP>4 </SUP>represents hydrogen, etc. and X represents a single bond or -CO-, etc.
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