发明名称 Hydrazide Derivatives
摘要 A compound represented by the following general formula (1) or a salt thereof or a hydrate of the foregoing is safe while exhibiting suitable physicochemical stability, and is useful as therapeutic or prophylactic agents for diseases associated with thrombus formation. wherein R<SUP>1a</SUP>, R<SUP>1b</SUP>, R<SUP>1c </SUP>and R<SUP>1d </SUP>each independently represent hydrogen, etc., R<SUP>2 </SUP>represents optionally substituted phenyl, etc., R<SUP>3 </SUP>represents optionally substituted C6-10 aryl, etc., Z<SUP>1</SUP>, Z<SUP>2 </SUP>and Z<SUP>3 </SUP>each independently represent hydrogen, etc., Z<SUP>4 </SUP>represents hydrogen, etc. and X represents a single bond or -CO-, etc.
申请公布号 US2008132507(A1) 申请公布日期 2008.06.05
申请号 US20050665385 申请日期 2005.10.13
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 CLARK RICHARD;HIROTA SHINSUKE;AZUMA HIROSHI;KIRA KAZUNOBU;WATANABE NOBUHISA;NAGAKURA TADASHI;HORIZOE TATSUO
分类号 A61K31/5375;A61K31/19;A61K31/381;A61K31/4192;A61K31/44;A61K31/47;A61K31/4965;A61K31/50;A61K31/505;A61P9/10;A61P11/00;C07C57/00;C07C63/00;C07D213/02;C07D215/00;C07D239/24;C07D241/10;C07D249/04;C07D295/00;C07D307/02;C07D333/02 主分类号 A61K31/5375
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