发明名称 |
BIS-( -AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE |
摘要 |
<p>The present invention provides biodegradable, biocompatible bis-(alpha-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.</p> |
申请公布号 |
EP1926780(A2) |
申请公布日期 |
2008.06.04 |
申请号 |
EP20060815378 |
申请日期 |
2006.09.22 |
申请人 |
MEDIVAS, LLC |
发明人 |
GOMURASHVILI, ZAZA, D.;HUGHES, JONATHAN, MACFERRAN;DA, JIE, NMN;ZHANG, HUASHI |
分类号 |
C08L77/00 |
主分类号 |
C08L77/00 |
代理机构 |
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代理人 |
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