发明名称 |
AMINOTETRAZOLE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS |
摘要 |
Compounds having formula (I) and pharmaceutically acceptable salts thereof, wherein B is NR5R11, wherein R5 is selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower alkynyl and aryl, and R11 is selected from a 3 to 8 member heterocyclyl radical in which at least one member of the ring is carbon and in which 1 to about 4 members are heteroatoms independently selected from oxygen, nitrogen and sulfur and said heterocyclyl radical may be optionally substituted, useful as nitric oxide synthase inhibitors.
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申请公布号 |
CA2203237(C) |
申请公布日期 |
2008.06.03 |
申请号 |
CA19952203237 |
申请日期 |
1995.11.08 |
申请人 |
G.D. SEARLE & CO. |
发明人 |
TSYMBALOV, SOFYA;HANSEN, DONALD W., JR.;HALLINAN, ANN E. |
分类号 |
C07D257/06;C12N9/99;A61K31/41;A61K31/415;A61K31/4168;A61K31/4196;A61K31/425;A61K31/426;A61K31/505;A61P9/00;A61P43/00;C07C257/14;C07D231/40;C07D233/88;C07D239/22;C07D239/42;C07D249/14;C07D277/18;C07D277/20;C07D277/46;C07D277/50 |
主分类号 |
C07D257/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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