发明名称 SYNTHESIS OF RENIN INHIBITORS INVOLVING A CYCLOADDITION REACTION
摘要 The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula (III), wherein R, R1, and R' are as defined in the specification, or a salt thereof, and a compound of formula (IV) wherein R, R1, R2 and R' are as defined in the specification, and processes of manufacturing these.
申请公布号 KR20080048042(A) 申请公布日期 2008.05.30
申请号 KR20087007396 申请日期 2008.03.27
申请人 NOVARTIS AG 发明人 MICKEL STUART JOHN;MARTERER WOLFGANG
分类号 C07C249/00;C07C251/24;C07D207/16 主分类号 C07C249/00
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