Use of agomelatine, to obtain a drug to treat Smith Magenis syndrome, major depression, seasonal depression, sleep disorder, cardiovascular disease, digestive system disorder, insomnia, shiftlag, appetite disorders and obesity
摘要
<p>Use of agomelatine (I) or its hydrates, crystalline forms and acid or base addition salts, to obtain a drug to treat Smith Magenis syndrome, is claimed. An independent claim is included for a composition comprising (I) optionally in combination with excipients. ACTIVITY : Antidepressant; Hypnotic; Cardiovascular-Gen.; Anorectic. MECHANISM OF ACTION : 5-Hydroxytryptamine-2C antagonist; Melatoninergic receptor agonist.</p>
